Comparative Survival after Trans-apical, Direct Aortic, and Subclavian Transcatheter Aortic Valve Implantation Data from the UK TAVI Registry Running title: Comparative Survival after non-femoral TAVI
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چکیده
Many patients have ilio-femoral vessel anatomy unsuitable for conventional trans-femoral (TF) trans-catheter aortic valve implantation (TAVI). Safe and practical alternatives to the TF approach are therefore needed. This study compared outcomes of alternative non-femoral routes, trans-apical (TA), direct aortic (DA) and subclavian (SC), with standard femoral access. In this retrospective study, data from 3,962 patients in the UK TAVI registry were analysed. All patients who received TAVI via a femoral, subclavian, transapical or direct aortic approach were eligible for inclusion. The primary outcome measure was survival up to two years. Median Logistic EuroSCORE was similar for SC, DA, and TA, but significantly lower in the TF Cox proportional hazard model was used to analyse survival up to 2-years. Survival in the SC group was not significantly different to the TF group01) cohorts was significantly reduced compared to TF. In conclusion, trans-apical and direct aortic TAVI were associated with similar survival, both significantly worse than with the trans-femoral route. In contrast, subclavian access was not significantly different to trans-femoral, and may represent the safest non-femoral access route for TAVI.
منابع مشابه
This is an author produced version of Comparative Survival after Trans-apical, Direct Aortic, and Subclavian Transcatheter Aortic Valve Implantation (Data from the UK TAVI
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تاریخ انتشار 2016